Babies = Disease Vectors

I'm on to my second cold in two weeks. I was happy that I didn't give Baby Girl my cold last week, but I'm sad to see it doesn't work the other way around: I caught my newest cold from her. Immunological properties of breast milk: 1  Me: 0.

The Air Up There: Taking the Fumes out of the Dreamliner

Check out my post on The Bill Nye Effect about Clem Furlong, an awesome researcher in Medical Genetics at the UW who does some interesting Toxicology field work with toxic fumes on airplanes.

While you're there, read some other postings on our blog!

Vicious Cycle

Like politics, research funding, and most everything else, life in the lab seems to run on a cycle. All of the visuals that come to mind-- a pendulum swinging left to right, the peaks and troughs of sinusoidal waves (or a roller coaster, for the less geeky)-- accurately describe the highs and lows of life. Sadly, the commonality of such patterns doesn't make the lows any easier to bear, nor the highs any more lasting.

Things were going well in the lab, and I guess overall, still are. Unfortunately for my sanity, there are still a few outlier experiments that should be working and aren't. And, as in the past, I have no idea why. This is the vicious cycle of lab research: knowing something is wrong but not knowing what it is, which makes it impossible to fix, and ultimately dooms you to repeat the mistakes. Until, perhaps, something magically changes. (Laugh if you will, but it's still the only explanation I have for my experiments beginning to work correctly back in March.)

I feel like a broken record saying all this, but it's so head-slamming-against-the-wall frustrating that I can't help but vent about it. Positive vibes are welcome these days, send them with care to the angry little lab rat.

I feel you, cat.

Feeling the Crunch

I'm having trouble deciding which time crunches in life are real and which are self-inflicted (and likely unnecessary). In my head, it's all about the next thing that has to be done, and it has to be done ASAP. No exceptions. That nagging voice telling me to work faster and walk quicker just doesn't quit. Maybe the academic environment is responsible for this: you're made to constantly worry about not producing enough data, or not fast enough (what if you get scooped?). What if your funding runs out? Many aspects of these things are not controllable, so the one thing that is-- your productivity-- becomes the main object of obsession.

I'm feel like I'm always late, and I'm unsure how important that date really is.

I walked out of a lab meeting today and was immediately stricken with a mix of anxiety and panic. My presented progress was sufficient this time around, so I left relatively unscathed. Regardless, my brain switched to scheduling the next 2 months+ of my lab life the instant I finished discussing my data. No matter how much progress I feel I made, or how hard I had worked in that past month, I ALWAYS walk out of the meeting overwhelmed by how much more I still need to do. Is this me being too hard on myself, or is this really just the reality of being a productive worker? When do you get to the point where you feel like you were productive enough?

For someone who really likes to strike a line through such things, mentally and physically, these lingering loose ends are guaranteed to induce panic. With the nature of lab work-- tedious, relying on cells to grow over the course of days and weeks-- I can't just rush to my desk and bust out the work that needs to be done. I am forced to sit and plan, and work for weeks to finish even one more experiment, one that may work to my benefit...or it may end more tragically (See: cell contamination). It's a horrible lesson in patience that I'm really tired of learning.

Women in Bio

Another great organization for networking with some powerful women in the biotech world and related: Women in Bio.

I went to one of their networking events last week and really enjoyed talking to so many successful, interesting women in the sciences. I tried to make some initial contacts and hope to see some of the same faces again. Especially for anyone on the East coast, this is a great org with some fun events. Check it out!

'Contagion:' Wash Your Hands

"Blogging is not writing. It's graffiti with punctuation." -Dr. Ian Sussman (Contagion)

For a rare night out, C and I went to see 'Contagion' this weekend. The film is frightening because of the subject matter, and jarring in its realism. It's straight-forward almost to the point of dryness, but for most people, uncontrollable viral epidemics are anything but. I loved it. 'Contagion' presents a situation in which a global epidemic occurs due to a series of random and completely plausible events. An unknown virus spreads rapidly through simple contact: touching surfaces on the bus, or sharing a bowl of peanuts at the bar. It's amazing how many things we touch that are in turn touched by millions of people. And then, as Kate Winslet's character points out, we go on to touch our faces some 2,000 times a day(!). Kate's character, as an aside, is sexy because a) she's Kate Winslet and b) because she has an awesome job at the CDC.

What I liked most about the film was its frankness, the reality of it all. There was no ridiculous drama, only understandable reactions of hungry, scared people who were left to fend for themselves due to lack of resources and a shut-down society. Government agencies, like the CDC, are portrayed as practical and even heroic (for once!). The reality of over-worked scientists and the fallible nature of even the most imposing leaders (Fishburne) were highlights in this aspect.


The characters are varied and excellent as well. Jude Law, for instance, plays the conspiracy-theorist, armed with a blog and millions of followers. He is not paranoid. He's smart, but distrustful of science and the government (as many are). His arguments are understandable and shared by many. Unfortunately, with the power of the Internet, he is able to convince people of an effective, alternative treatment for the virus (that's eventually disproved by science), and likely dissuades thousands of people from getting the vaccine. This character exists in real life. They truly believe in what they are saying and doing, and they reach A LOT of people who trust them. Look at what happened with the one misconducted study linking Autism to vaccines (data was forged, sample size was incredibly small, etc.) became popularized. Thankfully, it appears that Jenny McCarthy has since removed her epithets condemning vaccines and the government for requiring them.

For fellow lab rats, 'Contagion' hits all the right spots in its portrayal of lab science. Science is not magic. A vaccine to an unknown entity takes time to be developed. When they first try to make a vaccine in the movie, the virus kills every type of cell they put it in. Trial and error doesn't even begin to describe it. But, the look on the scientist's face when she realizes she does it-- she created a vaccine-- is priceless. It was that remarkable moment when the base-pairs align and your body fills with triumph. She quickly realizes that she needs to test it in humans immediately and, even in emergency situations, some clinical trials would have to be done before approval for mass use. Putting science first (in true devotee fashion) she injects herself with the vaccine. I wanted to cheer for her.

From the origins of the virus to its capacity to spread, the moral of the story was a true testament to the Public Health field: please, remember to wash your hands.

Is race influencing funding opportunities? Look closer.

Cross-posted from Secretlivesofscientists's Weblog::

Interesting commentary on the disparity of blacks funded by NIH grants. Thanks for using your analytical skills outside the lab, Em.